BCU INFECTION

BLOODSTREAM INFECTIONS - SEPSIS - BACTERAEMIA

Bloodstream infection, sepsis and further pathogen related infections that have proliferated in bloodstream is a major health problem worldwide, as well as infections correlated with haematogenous spread. Beside the impact on morbidity and mortality of the patient, pathogen related infections of the bloodstream are also a major cost factor to health care systems around the world.

The major challenges are the duration of pathogen identification, susceptibility testing and the fact that treatment has to start empirically before lab results are available. Clinical studies have demonstrated that adequate initial antibiotic treatment for most severe acute infections especially in case of severe sepsis and septic shock significantly improves medical outcome.
In addition, appropriate and early antibiotic selection will limit the risk of increasing antibiotic resistance in the population as a whole.

CAUSES OF BLOODSTREAM INFECTIONS
are manifold and could be released by the infecting agents such as bacteria and fungi. Blood cultures are the current gold standard to detect bacteria and fungal infections in bloodstream.

The culture of microorganisms is essential for the diagnosis of

  • Bloodstream infections
  • Bacteraemia
  • Fungaemia
  • Endocarditis
  • Prosthetic device infections
  • Pneumonia
  • Septic arthritis
  • Catheter related infections
  • e.g.